- Recommended name
- Gomiodomin B
- Synonyms
- Goniodomin-B
- Recommended acronym
- GDB
- Abbreviation
Progenitors
No progenitors registered
Vector Species
No vector species registered
- Structure
- Formula
- C43H60O12
- Exact mono-isotopic mass
- 768.41
- Molfile
- see other chem files
- Alternative molfiles
- n/a
- SMILES
- C=C([C@]2([H])CC[C@@](O2)([H])[C@@](O3)([H])C=CC[C@]37[H])[C@@H](O)[C@H](O)C\C=C/[C@H](OC([C@@](O4)([H])C(C[C@H]5[C@@]4([H])[C@@H](O6)C([C@H](C)C[C@@]6(C(CC[C@@H]7O)=C)O5)=C)=C)=O)[C@@]1(O)[C@H](C)[C@@H](C)CCO1
- Alternative SMILES
- n/a
- InChi key
- Alternative InChi keys
- n/a
- InChi
- Alternative InChis
- Spectra available
- True
- Chem files
References
- Harris et al., 2021
- GDB is probably not produced by dinoflagellates, but a rapid conversion product of GDA, i.e. an analytical artefact. See: Harris, C. M., B. Krock, U. Tillmann, C. J. Tainter, D. F. Stec, A. J. C. Andersen, T. O. Larsen, K. S. Reece and T. M. Harris (2021). "Alkali Metal- and Acid-Catalyzed Interconversion of Goniodomin A with Congeners B and C." Journal of Natural Products 84(9): 2554-2567.
- Certified
- False
- Certified links
-
-
n/a
- Non certified reference material
- False
Chemical analysis
- Research
- True
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
Structure recognition assays
- Research
- True
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
Functional assays
- Research
- Unknown
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
Animal assays
- Research
- Unknown
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
References
- Krock et al., 2018
- The compound described as GDB later turned out to be 34-desmethyl GDA. GDB is isobaric with GDA. See: Harris, C. M., L. Hintze, S. Gaillard, S. Tanniou, H. Small, K. S. Reece, U. Tillmann, B. Krock and T. M. Harris (2023). "Mass spectrometric characterization of the seco acid formed by cleavage of the macrolide ring of the algal metabolite goniodomin A." Toxicon 231: 107159.
- Regulatory status
- False
- Human toxic syndrome(s)
- n/a
- Organ system toxicity
- n/a
- Risk assessment
- Unknown
- Molecular targets known
- Unknown
- Molecular targets
- n/a
- Toxic to aquatic animals
- Unknown
- TEF available
- False
- Notes
- The structure of GDB published in Espiña et al., (2016) is incorrect Espiña, B., E. Cagide, M. C. Louzao, N. Vilariño, M. R. Vieytes, Y. Takeda, M. Sasaki and L. M. Botana (2016). "Cytotoxicity of goniodomin A and B in non contractile cells." Toxicology Letters 250–251: 10-20.
References
- Harris et al., 2021
- GDB is probably not produced by dinoflagellates, but a rapid conversion product of GDA, i.e. an analytical artefact. See: Harris, C. M., B. Krock, U. Tillmann, C. J. Tainter, D. F. Stec, A. J. C. Andersen, T. O. Larsen, K. S. Reece and T. M. Harris (2021). "Alkali Metal- and Acid-Catalyzed Interconversion of Goniodomin A with Congeners B and C." Journal of Natural Products 84(9): 2554-2567.
- Bernd Krock
- Contact